CTLA-4 / CD152 항체, 토끼 다클론항체

데이터시트리뷰프로토콜
발현 숙주: Human Cells  
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11159-H03H-200
11159-H03H-100
200 µg 
100 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
11159-H08H-200
11159-H08H-100
200 µg 
100 µg 
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발현 숙주: Human Cells  
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50503-M02H-200
50503-M02H-100
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100 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
50503-M08H-200
50503-M08H-100
200 µg 
100 µg 
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발현 숙주: Human Cells  
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81069-R02H-200
81069-R02H-100
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100 µg 
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발현 숙주: Human Cells  
  • Slide 1
81069-R08H-200
81069-R08H-100
200 µg 
100 µg 
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발현 숙주: Human Cells  
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90213-C02H-200
90213-C02H-100
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발현 숙주: Human Cells  
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90213-C08H-200
90213-C08H-100
200 µg 
100 µg 
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발현 숙주: Human Cells  
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70113-D08H-200
70113-D08H-100
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100 µg 
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발현 숙주: Human Cells  
  • Slide 1
70113-D02H-200
70113-D02H-100
200 µg 
100 µg 
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CTLA-4/CD152 ELISA Pair Set

검출 한계: 15.6 pg/ml
SEK11159-5
SEK11159-15
5 Plates 
15 Plates 
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CTLA-4/CD152 AntibodyRelated Products

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CTLA-4/CD152 antibody 연구배경

Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7-1) and CD86 (B7-2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role in their functions. CD152 or cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential receptor involved in the negative regulation of T cell activation. Because of its profound inhibitory role, CD152 has been considered a sound susceptible candidate in autoimmunity and a persuasive target for cancer immunotherapy. In particular, recent evidence suggests that CD152 is also important in the homeostasis and function of a population of suppressive cells, termed regulatory T cells (Treg).

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins   CTLA4 / CD152 Immune Checkpoint Proteins
Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

 CTLA-4/CD152 antibody 참고자료
  • Slavik JM, et al. (1999) CD28/CTLA-4 and CD80/CD86 families: signaling and function. Immunol Res. 19(1): 1-24.
  • Holmberg D, et al. (2005) CTLA-4 (CD152) and its involvement in autoimmune disease. Autoimmunity. 38(3): 225-33.
  • Chin LT, et al. (2008) Immune intervention with monoclonal antibodies targeting CD152 (CTLA-4) for autoimmune and malignant diseases. Chang Gung Med J. 31(1): 1-15.
  • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".