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IL3 / IL-3 항체, 토끼 다클론 항체, Antigen Affinity Purified

데이터시트리뷰프로토콜
제품 설명: Active  
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
11858-H08B-5
11858-H08B-20
11858-H08B-100
5 µg 
20 µg 
100 µg 
Add to Cart
발현 숙주: E. coli  
  • Slide 1
11858-HNAE-500
11858-HNAE-5
11858-HNAE-20
11858-HNAE-100
11858-HNAE-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
11858-H08H-50
11858-H08H-5
11858-H08H-100
11858-H08H-10
50 µg 
5 µg 
100 µg 
10 µg 
Add to Cart
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
80235-R08B-50
80235-R08B-20
50 µg 
20 µg 
Add to Cart

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IL3/IL-3/Interleukin-3 antibody 연구배경

IL3 (interleukin 3), also known as IL-3, is a potent growth promoting cytokine which belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

휴먼 IL3/IL-3/Interleukin-3 antibody 참고자료
  • Meyer CG, et al.. (2011) IL3 variant on chromosomal region 5q31-33 and protection from recurrent malaria attacks. Hum Mol Genet. 20(6):1173-81.
  • Zambrano A, et al. (2010) IL-3 controls tau modifications and protects cortical neurons from neurodegeneration. Curr Alzheimer Res. 7(7):615-24.
  • Dentelli P, et al.. (2011) IL-3 is a novel target to interfere with tumor vasculature. Oncogene. 30(50):4930-40.
  • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".