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VEGF / VEGFA 항체, 토끼 다클론 항체, Antigen Affinity Purified

데이터시트리뷰프로토콜
제품 설명: Active  
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
10009-HNAB-50
10009-HNAB-5
10009-HNAB-20
10009-HNAB-100
10009-HNAB-10
50 µg 
5 µg 
20 µg 
100 µg 
10 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
11066-HNAH-500
11066-HNAH-5
11066-HNAH-20
11066-HNAH-100
11066-HNAH-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
10008-HNAH-20
10008-HNAH-10
20 µg 
10 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
10008-HNAB-500
10008-HNAB-5
10008-HNAB-20
10008-HNAB-100
10008-HNAB-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
제품 설명: Active  
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
11066-HNAB-500
11066-HNAB-5
11066-HNAB-20
11066-HNAB-100
11066-HNAB-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
15692-HNAH-50
15692-HNAH-20
50 µg 
20 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
50159-MNAB-500
50159-MNAB-5
50159-MNAB-20
50159-MNAB-100
50159-MNAB-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
제품 설명: Active  
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
80006-RNAB-5
80006-RNAB-20
80006-RNAB-100
5 µg 
20 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
70004-DNAH-20
70004-DNAH-10
20 µg 
10 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
63004-ZNAB-5
63004-ZNAB-20
63004-ZNAB-100
5 µg 
20 µg 
100 µg 
Add to Cart

HP100106 

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VEGF/VEGFA antibody 연구배경

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

 VEGF/VEGFA antibody 참고자료
  • Woolard J. et al. (2004) VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression. Cancer Res. 64(21): 7822-7835.
  • Jia SF, et al. (2008) VEGF165 is necessary to the metastatic potential of Fas(-) osteosarcoma cells but will not rescue the Fas(+) cells. J Exp Ther Oncol. 7(2): 89-97.
  • Cimpean AM, et al. (2008) Vascular endothelial growth factor A (VEGF A) as individual prognostic factor in invasive breast carcinoma. Rom J Morphol Embryol. 49(3): 303-8.
  • Hamdollah Zadeh MA, et al. (2008) VEGF-mediated elevated intracellular calcium and angiogenesis in human microvascular endothelial cells in vitro are inhibited by dominant negative TRPC6. Microcirculation. 15(7): 605-14.
  • Eisenach PA, et al. (2010) MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src. J Cell Sci. 123(Pt 23):4182-4193.
  • Claesson-Welsh L (2010) Gremlin: vexing VEGF receptor agonist. Blood. 116(18):3386-7.
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