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HER2 / ErbB2 항체, 토끼 다클론 항체, Antigen Affinity Purified

데이터시트리뷰프로토콜
발현 숙주: Human Cells  
  • Slide 1
10004-HCCH-50
10004-HCCH-200
50 µg 
200 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
10004-H08H-50
10004-H08H-100
50 µg 
100 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
10004-H02H-50
10004-H02H-100
50 µg 
100 µg 
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발현 숙주: Baculovirus-Insect Cells  
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10004-H20B1-50
10004-H20B1-20
10004-H20B1-10
50 µg 
20 µg 
10 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
10004-H08H1-50
10004-H08H1-200
50 µg 
200 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
10004-H08H4-50
10004-H08H4-200
50 µg 
200 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
50714-M02H-50
50714-M02H-100
50 µg 
100 µg 
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발현 숙주: Human Cells  
  • Slide 1
50714-M08H-50
50714-M08H-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
80079-R02H-50
80079-R02H-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
80079-R08H-50
80079-R08H-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
80079-RCCH-50
80079-RCCH-20
50 µg 
20 µg 
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발현 숙주: Human Cells  
  • Slide 1
90295-C08H-50
90295-C08H-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
90295-C02H-50
90295-C02H-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
70024-D08H-50
70024-D08H-100
50 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
90020-K02H-50
90020-K02H-100
50 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
90020-K08H-50
90020-K08H-100
50 µg 
100 µg 
Add to Cart

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HER2/ERBB2 antibody 연구배경

Epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

 HER2/ERBB2 antibody 참고자료
  • Krawczyk N, et al. (2009) HER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumor. Anticancer Res. 29(10): 4019-24.
  • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".