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FOP / FGFR1OP 항체, 토끼 다클론 항체, Antigen Affinity Purified

데이터시트리뷰프로토콜
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
14414-H20B-20
14414-H20B-100
20 µg 
100 µg 
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FOP / FGFR1OP antibody 연구배경

FOP( fibroblast growth factor receptor 1 oncogene partner) is a largely hydrophilic protein postulated to be a leucine-rich protein family member. FOP contains 1 LisH domain. A t(6;8)(q27;p11) chromosomal translocation, fusing FOP gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. FOP gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.

휴먼 FOP / FGFR1OP antibody 참고자료
  • Reither A. et al., 1999, Med Klin (Munich). 94 (4): 207-10.
  • Guasch G. et al., 2004, Blood. 103 (1): 309-12.
  • Popovici C. et al., 1999, Blood. 93 (4): 1381-9.
  • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".