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HER3 / ErbB3 항체, 토끼 다클론 항체, Antigen Affinity Purified

데이터시트리뷰프로토콜
발현 숙주: Human Cells  
  • Slide 1
10201-H05H-50
10201-H05H-100
50 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
10201-H20B1-50
10201-H20B1-20
50 µg 
20 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
10201-H08H-50
10201-H08H-20
10201-H08H-10
50 µg 
20 µg 
10 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
10201-HCCH-50
10201-HCCH-200
50 µg 
200 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
10201-H02H-50
10201-H02H-100
50 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
51003-M08H-50
51003-M08H-100
50 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
80111-R02H-50
80111-R02H-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
80111-R08H-50
80111-R08H-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
90043-KCCH-50
90043-KCCH-100
50 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
90043-K08H-50
90043-K08H-100
50 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
90043-K02H-50
90043-K02H-100
50 µg 
100 µg 
Add to Cart

ERBB3/HER3 ELISA Pair Set

검출 한계: 23.44 pg/ml
SEK10201-5
SEK10201-15
5 Plates 
15 Plates 
Add to Cart
검출 한계:
SEK51003-5
SEK51003-15
5 Plates 
15 Plates 
Add to Cart

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ERBB3/HER3 antibody 연구배경

ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity, and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicated in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

휴먼 ERBB3/HER3 antibody 참고자료
주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".