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Carboxypeptidase B1 / CPB1 항체, 생쥐 단클론항체

데이터시트리뷰프로토콜
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
10501-H08H-20
10501-H08H-10
20 µg 
10 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
50386-M08H-20
50386-M08H-10
20 µg 
10 µg 
Add to Cart

Carboxypeptidase B1/CPB1 ELISA Pair Set

검출 한계: 6.25 pg/ml
SEK10501-5
SEK10501-15
5 Plates 
15 Plates 
Add to Cart
검출 한계: 12.5 pg/ml
SEK50386-5
SEK50386-15
5 Plates 
15 Plates 
Add to Cart

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Carboxypeptidase B1/CPB1 antibody 연구배경

Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 307-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin.

휴먼 Carboxypeptidase B1/CPB1 antibody 참고자료
  • Yamamoto, K.K. et al., 1992, J. Biol. Chem. 267: 2575-2581.
  • Pezzilli, R. et al., 1994, Digestion. 55: 73-77.
  • Barbosa Pereira, P.J. et al., 2002, J. Mol. Biol. 321: 537-547.
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