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쥐 IL-5/IL5 / Interleukin 5 Gene ORF cDNA clone expression plasmid

데이터시트리뷰프로토콜
제품 설명:   
발현 숙주: E. coli  
  • Slide 1
15673-HNCE-5
15673-HNCE-20
15673-HNCE-100
5 µg 
20 µg 
100 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
51068-M08B-5
51068-M08B-20
51068-M08B-100
5 µg 
20 µg 
100 µg 
Add to Cart
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
70019-D08B-5
70019-D08B-20
70019-D08B-100
5 µg 
20 µg 
100 µg 
Add to Cart
반응성: Human  
신청: 
  • Slide 1
15673-R013-500
15673-R013-200
500 µg 
200 µg 
Add to Cart
반응성: Human  
신청: 
    15673-MM13-50
    15673-MM13-200
    15673-MM13-100
    15673-MM13-1
    50 µg 
    200 µg 
    100 µg 
    1 mg 
    Add to Cart
    반응성: Human  
    신청: ELISA  
      15673-MM02-50
      15673-MM02-200
      15673-MM02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Human  
      신청: ELISA  WB  
      • Slide 1
      15673-T48-50
      15673-T48-200
      15673-T48-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Mouse  
      신청: 
        51068-R121-50
        51068-R121-100
        50 µg 
        100 µg 
        Add to Cart
        반응성: Mouse  
        신청: ELISA  
          51068-T16-50
          51068-T16-200
          51068-T16-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          반응성: Mouse  
          신청: ELISA  WB  
          • Slide 1
          51068-T48-50
          51068-T48-200
          51068-T48-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          반응성: Mouse  
          신청: ELISA  
            51068-RP01-400
            51068-RP01-200
            51068-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            반응성: Canine  
            신청: ELISA  
              70019-RP01-400
              70019-RP01-200
              70019-RP01-100
              400 µg 
              200 µg 
              100 µg 
              Add to Cart

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              IL-5/IL5 / Interleukin 5 cdna-clone 연구배경

              Interleukin 5 (IL-5) is a member of the interleukin family with length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins / signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered as a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues, and can modulate eosinophil behavior at every stage from maturation to survival.

               IL-5/IL5 / Interleukin 5 cdna-clone 참고자료
            • Milburn MV, et al. (1993) A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5. Nature. 363(6425): 172-176.
            • Lee JS, et al. (1989) The IL-4 and IL-5 genes are closely linked and are part of a cytokine gene cluster on mouse chromosome 11. Somat Cell Mol Genet. 15(2): 143-152.
            • Woodcock JM, et al. (1994) Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. EMBO J. 13 (21): 5176-85.
            • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".