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쥐 IL17A/IL-17A/IL17 Gene ORF cDNA clone expression plasmid

데이터시트리뷰프로토콜
발현 숙주: Yeast  
  • Slide 1
12047-H07Y-50
12047-H07Y-100
50 µg 
100 µg 
Add to Cart
발현 숙주: E. coli  
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12047-HNAE-5
12047-HNAE-20
12047-HNAE-100
5 µg 
20 µg 
100 µg 
Add to Cart
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
12047-H07B-50
12047-H07B-5
12047-H07B-20
12047-H07B-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
발현 숙주: CHO Stable Cells  
  • Slide 1
12047-HNAS-500
12047-HNAS-5
12047-HNAS-20
12047-HNAS-100
12047-HNAS-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
제품 설명: Active  
발현 숙주: E. coli  
  • Slide 1
51065-MNAE-50
51065-MNAE-20
50 µg 
20 µg 
Add to Cart
발현 숙주: E. coli  
  • Slide 1
70102-DNAE-50
70102-DNAE-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
90306-KNAB-20
90306-KNAB-100
20 µg 
100 µg 
Add to Cart
제품 설명:   
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
65006-T07B-5
65006-T07B-20
65006-T07B-100
5 µg 
20 µg 
100 µg 
Add to Cart
반응성: Human  
신청: ELISA  
    12047-MM06-50
    12047-MM06-200
    12047-MM06-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    반응성: Human  
    신청: 
      12047-MM06T-50
      12047-MM06T-200
      12047-MM06T-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Human  
      신청: B/N  
      • Slide 1
      12047-M237-500
      12047-M237-200
      500 µg 
      200 µg 
      Add to Cart
      반응성: Human  
      신청: ELISA  
        12047-T16-50
        12047-T16-200
        12047-T16-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        반응성: Mouse  
        신청: ELISA  
          51065-R215-50
          51065-R215-100
          51065-R215-1
          50 µg 
          100 µg 
          1 mg 
          Add to Cart
          반응성: Mouse  
          신청: ELISA  
            51065-RP01-400
            51065-RP01-200
            51065-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            반응성: Mouse  
            신청: ELISA  
              51065-T16-50
              51065-T16-200
              51065-T16-100
              50 µg 
              200 µg 
              100 µg 
              Add to Cart

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              IL17A/IL-17A/IL17 cdna-clone 연구배경

              IL17, also known as IL17a, is a cytokine belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

              Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

               IL17A/IL-17A/IL17 cdna-clone 참고자료
            • Andoh A, et al. (2002) IL-17 selectively down-regulates TNF-alpha-induced RANTES gene expression in human colonic subepithelial myofibroblasts. J Immunol. 169(4):1683-7.
            • Kotake S, et al. (1999) IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest. 103(9):1345-52.
            • Laan M, et al. (1999) Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. J Immunol. 162(4):2347-52.
            • Shin HC, et al. (1999) Regulation of IL-17, IFN-gamma and IL-10 in human CD8(+) T cells by cyclic AMP-dependent signal transduction pathway. Cytokine. 10(11):841-50.
            • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".