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쥐 BLBP/FABP7 Gene ORF cDNA clone expression plasmid

데이터시트리뷰프로토콜
발현 숙주: E. coli  
  • Slide 1
12577-HNAE-20
12577-HNAE-100
20 µg 
100 µg 
Add to Cart
반응성: Human  
신청: ELISA  WB  
  • Slide 1
12577-T48-50
12577-T48-200
12577-T48-100
50 µg 
200 µg 
100 µg 
Add to Cart

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BLBP/FABP7 cdna-clone 연구배경

BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake, transport, and metabolism. BLBP is expressed, during development, in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. BLBP variation is linked to weak prepulse inhibition(PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives.

 BLBP/FABP7 cdna-clone 참고자료
  • Shi YE, et al. (1997) Antitumor activity of the novel human breast cancer growth inhibitor, mammary-derived growth inhibitor-related gene, MRG. Cancer Res. 57(15):3084-91.
  • Young JK, et al. (1997) Immunoreactivity for brain-fatty acid binding protein in gomori-positive astrocytes. Glia. 16(3):218-26.
  • Xu LZ, et al. (1996) Ligand specificity of brain lipid-binding protein. J Biol Chem. 271(40): 24711-9.
  • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".