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휴먼 CXADR / CAR Gene ORF cDNA clone expression plasmid, N-Flag 태그

데이터시트리뷰프로토콜
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10799-H08H-50
10799-H08H-100
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100 µg 
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10799-H03H-50
10799-H03H-100
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100 µg 
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발현 숙주: Human Cells  
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50019-MCCH-50
50019-MCCH-20
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20 µg 
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발현 숙주: Human Cells  
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50019-M03H-50
50019-M03H-100
50 µg 
100 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
50019-M08H-50
50019-M08H-100
50 µg 
100 µg 
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발현 숙주: Human Cells  
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50019-M03H1-50
50019-M03H1-200
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200 µg 
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반응성: Human  
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    10799-RP01-400
    10799-RP01-200
    10799-RP01-100
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    200 µg 
    100 µg 
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    반응성: Human  
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      10799-R020-50
      10799-R020-100
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      반응성: Human  
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        10799-R023-50
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        10799-R023-1
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        신청: FCM  
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        10799-R271-F-25
        10799-R271-F-100
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        신청: ELISA  
          10799-R068-50
          10799-R068-100
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          100 µg 
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          반응성: Human  
          신청: FCM  IF  ICC/IF  
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          10799-R271-50
          10799-R271-100
          10799-R271-1
          50 µg 
          100 µg 
          1 mg 
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          반응성: Human  
          신청: FCM  
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          10799-R271-P-25
          10799-R271-P-100
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          반응성: Human  
          신청: ELISA  
            10799-RP02-50
            10799-RP02-200
            10799-RP02-100
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            200 µg 
            100 µg 
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            반응성: Mouse  
            신청: ELISA  
              50019-RP01-400
              50019-RP01-200
              50019-RP01-100
              400 µg 
              200 µg 
              100 µg 
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              반응성: Mouse  
              신청: ELISA  IHC-P  
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              50019-R001-50
              50019-R001-100
              50 µg 
              100 µg 
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              반응성: Mouse  
              신청: ELISA  IHC-P  
              • Slide 1
              • Slide 1
              50019-RP02-50
              50019-RP02-200
              50019-RP02-100
              50 µg 
              200 µg 
              100 µg 
              Add to Cart

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              CXADR / CAR cdna-clone 연구배경

              CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I  transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 107 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 90% sequence identity with the corresponding regions of rat, human CXADR.

              휴먼 CXADR / CAR cdna-clone 참고자료
            • Tomko, R.P. et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94 (7): 3352–3356.
            • van Raaij , M.J. et al., 2001, Structure. 8 (11): 1147–1155.
            • Cohen, C.J. et al., 2001, J. Biol. Chem. 276 (27): 25392–25398.
            • Carson, S.D. et al., 2002, Rev. Med. Virol. 11 (4): 219–226.
            • Selinka, H.C. et al., 2004, Med. Microbiol. Immunol. 193 (2-3): 127–131.
            • Philipson, L. et al., 2004, Curr. Top. Microbiol. Immunol. 273:87-111.
            • Raschperger, E. et al., 2006, Exp. Cell Res. 312: 1566-1580.
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