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휴먼 CD10/Neprilysin Gene ORF cDNA clone expression plasmid, N-Flag 태그

데이터시트리뷰프로토콜
제품 설명: Active  
발현 숙주: Human Cells  
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10805-H01H-20
10805-H01H-10
20 µg 
10 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
10805-H07H-20
10805-H07H-10
20 µg 
10 µg 
Add to Cart
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
10805-HNCH-20
10805-HNCH-10
20 µg 
10 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
50218-M07H-20
50218-M07H-10
20 µg 
10 µg 
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발현 숙주: Human Cells  
  • Slide 1
80288-R07H-20
80288-R07H-10
20 µg 
10 µg 
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반응성: Human  
신청: ELISA  
    10805-MM05-50
    10805-MM05-200
    10805-MM05-100
    50 µg 
    200 µg 
    100 µg 
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    반응성: Human  
    신청: IF  ICC/IF  
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    100390-T02-50
    100390-T02-200
    100390-T02-100
    50 µg 
    200 µg 
    100 µg 
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    반응성: Human  
    신청: FCM  
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    10805-MM05-P-25
    10805-MM05-P-100
    25 Test 
    100 Tests 
    Add to Cart
    반응성: Mouse  
    신청: ELISA  
      50218-T16-50
      50218-T16-200
      50218-T16-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Rhesus  
      신청: ELISA  WB  IHC-P  IP  
      • Slide 1
      • Slide 1
      • Slide 1
      • Slide 1
      90177-T60-50
      90177-T60-200
      90177-T60-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart

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      CD10/Neprilysin cdna-clone 연구배경

      The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had function to degrade a number of small secreted peptides such as the amyloid beta peptide. It exist as a membrane-bound protein and have high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes.

      휴먼 CD10/Neprilysin cdna-clone 참고자료
    • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
    • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
    • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12
    • Dogan, et al. (2000) CD10 and BCL-6 Expression in Paraffin Sections of Normal Lymphoid Tissue and B-Cell Lymphomas. American Journal of Surgical Pathology. 24(6): 846-52.
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