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휴먼 LILRA3/CD85e/ILT6 Gene ORF cDNA clone expression plasmid, C-Flag 태그

데이터시트리뷰프로토콜
발현 숙주: Human Cells  
  • Slide 1
13549-H08H-20
13549-H08H-100
20 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
13549-H02H-50
13549-H02H-20
13549-H02H-100
50 µg 
20 µg 
100 µg 
Add to Cart
반응성: Human  
신청: ELISA  
    13549-RP01-400
    13549-RP01-200
    13549-RP01-100
    400 µg 
    200 µg 
    100 µg 
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    반응성: Human  
    신청: ELISA  
      13549-T16-50
      13549-T16-200
      13549-T16-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Human  
      신청: ELISA  
        13549-MM06-50
        13549-MM06-200
        13549-MM06-100
        13549-MM06-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
        Add to Cart

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        LILRA3/CD85e/ILT6 cdna-clone 연구배경

        ILT6, also known as LILRA3, belongs to the ILT family. In human, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immuno-globulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.

        휴먼 LILRA3/CD85e/ILT6 cdna-clone 참고자료
      • Wi?niewski A, et al. (2004) Distribution of LILRA3 (ILT6 / LILRA3/LIR4) deletion in psoriatic patients and healthy controls. Hum Immunol. 64(4):458-61.
      • Norman PJ, et al. (2003) DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3. Immunogenetics. 55(3):165-71.
      • Cella M, et al. (1997) A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing. J Exp Med. 185(10): 1743-51.
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