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휴먼 14-3-3 sigma/Stratifin/YWHAS Gene ORF cDNA clone expression plasmid, N-Flag 태그

데이터시트리뷰프로토콜
발현 숙주: E. coli  
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10838-H09E-20
10838-H09E-100
20 µg 
100 µg 
Add to Cart
발현 숙주: E. coli  
  • Slide 1
10838-HNCE-200
10838-HNCE-100
200 µg 
100 µg 
Add to Cart
발현 숙주: E. coli  
  • Slide 1
50576-MNCE-50
50576-MNCE-100
50 µg 
100 µg 
Add to Cart
반응성: Human  
신청: 
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  • Slide 1
  • Slide 1
10838-T54-50
10838-T54-200
10838-T54-100
50 µg 
200 µg 
100 µg 
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반응성: Human  
신청: ELISA  
    10838-RP01-400
    10838-RP01-200
    10838-RP01-100
    400 µg 
    200 µg 
    100 µg 
    Add to Cart
    반응성: Human  
    신청: ELISA  
      10838-RP02-50
      10838-RP02-200
      10838-RP02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Human  
      신청: FCM  
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      10838-MM02-P-25
      10838-MM02-P-100
      25 Test 
      100 Tests 
      Add to Cart
      반응성: Human  
      신청: FCM  
      • Slide 1
      10838-MM02-50
      10838-MM02-200
      10838-MM02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Mouse  
      신청: ELISA  WB  IHC-P  IP  
      • Slide 1
      • Slide 1
      • Slide 1
      50576-RP02-50
      50576-RP02-200
      50576-RP02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Mouse  
      신청: ELISA  
        50576-RP01-400
        50576-RP01-200
        50576-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart

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        14-3-3 sigma/Stratifin/YWHAS cdna-clone 연구배경

        14-3-3 protein sigma (YWHAS), also known as stratifin (SFN) and epithelial cell marker protein 1, is a member of the14-3-3 proteins which are a family of conserved regulatory molecules expressed in all eukaryotic cells. The name 14-3-3 refers to the particular elution and migration pattern of these proteins on DEAE-cellulose chromatography and starch-gel electrophoresis. The 14-3-3 proteins eluted in the 14th fraction of bovine brain homogenate and were found on positions 3.3 of subsequent electrophoresis. There are seven genes that encode 14-3-3s in most mammals. 14-3-3 proteins have been identified as adapter proteins implicated in the regulation of a large spectrum of both general and specialized signaling pathway. More than 100 signaling proteins have been reported as 14-3-3 ligands including kinases, phosphatases, and transmembrane receptors, and the binding generally results in the modulation of the activity of the binding partner. YWHAE exists as a homodimer and present mainly in tissues enriched in stratified squamous keratinising epithelium. YWHAS has been repoted to interact with KRT17 and GAB2, and may regulate protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway upon binding to KRT17. Additionally, YWHAS (SFN) may also act as a p53-regulated inhibitor of G2/M progression.

        휴먼 14-3-3 sigma/Stratifin/YWHAS cdna-clone 참고자료
        주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".