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휴먼 Neurexophilin-1/NXPH1 Gene ORF cDNA clone expression plasmid, N-Flag 태그

데이터시트리뷰프로토콜
발현 숙주: Human Cells  
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50865-M08H-50
50865-M08H-100
50 µg 
100 µg 
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발현 숙주: Human Cells  
  • Slide 1
80047-R08H-50
80047-R08H-100
50 µg 
100 µg 
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반응성: Rat  
신청: ELISA  
    80047-RP01-400
    80047-RP01-200
    80047-RP01-100
    400 µg 
    200 µg 
    100 µg 
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    반응성: Rat  
    신청: IHC-P  
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    • Slide 1
    80047-R001-50
    80047-R001-100
    50 µg 
    100 µg 
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    반응성: Rat  
    신청: ELISA  
      80047-R021-50
      80047-R021-100
      50 µg 
      100 µg 
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      반응성: Rat  
      신청: ELISA  
        80047-T16-50
        80047-T16-200
        80047-T16-100
        50 µg 
        200 µg 
        100 µg 
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        Neurexophilin-1/NXPH1 cdna-clone 연구배경

        Neurexophilin-1, or NXPH1 is a secreted glycoprotein, which belongs to the Neurexophilin family. The Neurexophilin family contain at least four genes and resembles a neuropeptide, suggesting a function as an endogenous ligand for alpha-neurexins. The mammalian brains contain four genes for neurexophilins the products of which share a common structure composed of five domains: an N-terminal signal peptide, a variable N-terminal domain, a highly conserved central domain that is N-glycosylated, a short linker region, and a conserved C-terminal domain that is cysteine-rich. Neurexophilin-1 constitutes a secreted cysteine-rich glycoprotein, forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. Neurexophilins 1 and 3 but not 4 (neurexophilin 2 is not expressed in rodents) bind to a single individual LNS domain, the second overall LNS domain in all three alpha-neurexins.

        휴먼 Neurexophilin-1/NXPH1 cdna-clone 참고자료
      • Missler M, et al. (1998) Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit. J Biol Chem. 273(52): 34716-23.
      • Missler M, et al. (1998) Neurexophilins form a conserved family of neuropeptide-like glycoproteins. J Neurosci. 18(10): 3630-8.
      • Petrenko AG, et al. (1996) Structure and evolution of neurexophilin. J Neurosci. 16(14): 4360-9.
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