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휴먼 LAIR2 (CD306) Gene ORF cDNA clone expression plasmid, N-Flag 태그

데이터시트리뷰프로토콜
제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
10868-H08H-50
10868-H08H-100
50 µg 
100 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
10868-HNAH-50
10868-HNAH-100
50 µg 
100 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
10868-HNAH-E-5
10868-HNAH-E-10
5 µg 
10 µg 
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반응성: Human  
신청: ELISA  
    10868-RP01-400
    10868-RP01-200
    10868-RP01-100
    400 µg 
    200 µg 
    100 µg 
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    반응성: Human  
    신청: 
      10868-R001-50
      10868-R001-100
      10868-R001-1
      50 µg 
      100 µg 
      1 mg 
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      반응성: Human  
      신청: ELISA  
        10868-RP02-50
        10868-RP02-200
        10868-RP02-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        반응성: Human  
        신청: ELISA  
          10868-R024-50
          10868-R024-100
          50 µg 
          100 µg 
          Add to Cart

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          LAIR2 (CD306) cdna-clone 연구배경

          Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD306, is a 131 amino acid protein containing one lg-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.

          휴먼 LAIR2 (CD306) cdna-clone 참고자료
        • Meyaard, L. et al.,1997, Immunity.7:283-290.
        • Meyaard, L. et al.,1999, J. Immunol. 162:5800-5804.
        • Meyaard, L. et al., 2001,  J. Exp. Med. 194 (1): 107-112.
        • Meyaard, L., 2003, J Biol Regul Homeost Agents.  17 (4): 330-333.
        • Lebbink, R. J. et al., 2008, J Immunol. 180 (3):1662-1669.
        • Lebbink,R.J. et al., 2009,  Matrix Biol.  28 (4):202-210.
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