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휴먼 NAP-2 / PPBP / CXCL7 Gene ORF cDNA clone expression plasmid, N-Flag 태그

데이터시트리뷰프로토콜
발현 숙주: E. coli  
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10878-H07E-50
10878-H07E-20
50 µg 
20 µg 
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발현 숙주: E. coli  
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50145-M07E-20
50145-M07E-10
20 µg 
10 µg 
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발현 숙주: E. coli  
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50145-M07E1-20
50145-M07E1-10
20 µg 
10 µg 
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발현 숙주: Yeast  
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80066-R08Y-20
80066-R08Y-100
20 µg 
100 µg 
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발현 숙주: Human Cells  
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80066-R01H-20
80066-R01H-10
20 µg 
10 µg 
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발현 숙주: Human Cells  
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90132-C04H-20
90132-C04H-10
20 µg 
10 µg 
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발현 숙주: Yeast  
  • Slide 1
90132-C08Y-20
90132-C08Y-100
20 µg 
100 µg 
Add to Cart
반응성: Human  
신청: ELISA  
    10878-RP01-400
    10878-RP01-200
    10878-RP01-100
    400 µg 
    200 µg 
    100 µg 
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    반응성: Human  
    신청: ELISA  
      10878-T16-50
      10878-T16-200
      10878-T16-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Mouse  
      신청: ELISA  WB  IP  
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      50145-T52-50
      50145-T52-200
      50145-T52-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart

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      NAP-2 / PPBP / CXCL7 cdna-clone 연구배경

      Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activation and is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Nap-2 / PPBP / CXCL7 has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Nap-2 is a ligand for CXCR1 and CXCR2, and Nap-2, Nap-2 (73), Nap-2 (74), Nap-2 (1-66), and most potent Nap-2 (1-63) are chemoattractants and activators for neutrophils.

      Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

      휴먼 NAP-2 / PPBP / CXCL7 cdna-clone 참고자료
    • Walz A, et al. (1989) Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophils. J Exp Med. 170(5):1745-50.
    • Walz A, et al. (1990) Generation of the neutrophil-activating peptide NAP-2 from platelet basic protein or connective tissue-activating peptide III through monocyte proteases. J Exp Med. 171(2): 449-54.
    • Loetscher P, et al. (1994) Both interleukin-8 receptors independently mediate chemotaxis. Jurkat cells transfected with IL-8R1 or IL-8R2 migrate in response to IL-8, GRO alpha and NAP-2. FEBS Lett. 341(2-3): 187-92.
    • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".