Text Size:AAA

휴먼 ENPP7 Gene ORF cDNA clone expression plasmid, N-Flag 태그

데이터시트리뷰프로토콜
발현 숙주: Human Cells  
  • Slide 1
10885-H08H-20
10885-H08H-10
20 µg 
10 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
50567-M08H-20
50567-M08H-10
20 µg 
10 µg 
Add to Cart
반응성: Human  
신청: IF  ICC/IF  
  • Slide 1
10885-MM10-50
10885-MM10-200
10885-MM10-100
50 µg 
200 µg 
100 µg 
Add to Cart
반응성: Human  
신청: ELISA  
    10885-R001-50
    10885-R001-100
    50 µg 
    100 µg 
    Add to Cart
    반응성: Human  
    신청: ELISA  
      10885-MM02-50
      10885-MM02-200
      10885-MM02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      반응성: Human  
      신청: ELISA  
        10885-RP01-400
        10885-RP01-200
        10885-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        반응성: Human  
        신청: ELISA  WB  
        • Slide 1
        10885-RP02-50
        10885-RP02-200
        10885-RP02-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart

        ENPP7 cDNA ORF CloneRelated Products

        Related Products

        Featured Reagent Products

        ENPP7 cdna-clone 연구배경

        Ectonucleotide pyrophosphatase / phosphodiesterase family member 7, also known as Alkaline sphingomyelin phosphodiesterase, Intestinal alkaline sphingomyelinase, Alk-Smase, ENPP7 and NPP-7, is a single-pass type I membrane protein which belongs to the nucleotide pyrophosphatase / phosphodiesterase family. ENPP7 / NPP-7 is expressed in the intestines and human bile. ENPP7 / NPP-7 is localized at the surface of the microvillar membrane in small intestine enterocytes, as well as in endosome-like structures and in Golgi complex. The main function of ENPP7 / NPP-7 is to convert the dietary sphingomyelin into ceramide, the sphingolipid messengers via hydrolyzation. ENPP7 / NPP-7 is also reported to exert a phospholipase C activity toward palmitoyl lyso-phosphocholine. The activity of this enzyme is inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Further, It has been shown in studies that decreased levels of ENPP7 / NPP-7 may be associated with human colon cancer.

        휴먼 ENPP7 cdna-clone 참고자료
      • Wu J. et al., 2005, Biochem. J. 386:153-60.
      • Wu J. et al., 2004, Carcinogenesis 25:1327-33.
      • Duan R.-D. et al., 2003, J. Lipid Res. 44:1241-50.
      • Duan R.-D. et al., 2003, J. Biol. Chem. 278:38528-36.
      • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".