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휴먼 CXCL5 Gene ORF cDNA clone expression plasmid, N-Flag 태그

데이터시트리뷰프로토콜
발현 숙주: E. coli  
  • Slide 1
10889-HNAE-50
10889-HNAE-20
50 µg 
20 µg 
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발현 숙주: Yeast  
  • Slide 1
50354-M08Y-20
50354-M08Y-100
20 µg 
100 µg 
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반응성: Human  
신청: ELISA  
    10889-RP01-400
    10889-RP01-200
    10889-RP01-100
    400 µg 
    200 µg 
    100 µg 
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    반응성: Human  
    신청: ELISA  IHC-P  
    • Slide 1
    10889-T24-50
    10889-T24-200
    10889-T24-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    반응성: Human  
    신청: IHC-P  
    • Slide 1
    10889-T08-50
    10889-T08-200
    10889-T08-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart

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    CXCL5 cdna-clone 연구배경

    CXCL5 is a small cytokine belonging to the CXC chemokine family. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. CXCL5 is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. It also can be detected in eosinophils, and can be inhibited with the type II interferon. CXCL5 plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which can be utilized to understand more about pain in other inflammatory conditions like arthritis and cystitis. It stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2.

    휴먼 CXCL5 cdna-clone 참고자료
  • Dawes JM, et al. (2011) CXCL5 Mediates UVB Irradiation-Induced Pain. Sci Transl Med. 3(90): 90ra60.
  • O'Donovan N, et al. (1999) Physical mapping of the CXC chemokine locus on human chromosome 4. Cytogenet. Cell Genet. 84(1-2):39-42.
  • Persson T, et al. (2003) Expression of the neutrophil-activating CXC chemokine ENA-78/CXCL5 by human eosinophils. Clin Exp Allergy. 33(4):531-7.
  • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".