Text Size:AAA

휴먼 BAMBI/NMA Gene ORF cDNA clone expression plasmid, N-Flag 태그

데이터시트리뷰프로토콜
발현 숙주: Human Cells  
  • Slide 1
10890-H08H-50
10890-H08H-20
50 µg 
20 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
50895-M02H-50
50895-M02H-20
50 µg 
20 µg 
Add to Cart
발현 숙주: Human Cells  
  • Slide 1
50895-M08H-50
50895-M08H-20
50 µg 
20 µg 
Add to Cart
반응성: Human  
신청: ELISA  
    10890-MM06-50
    10890-MM06-200
    10890-MM06-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    반응성: Human  
    신청: 
      10890-MM10-50
      10890-MM10-200
      10890-MM10-100
      10890-MM10-1
      50 µg 
      200 µg 
      100 µg 
      1 mg 
      Add to Cart
      반응성: Human  
      신청: 
        10890-MM02-50
        10890-MM02-200
        10890-MM02-100
        10890-MM02-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
        Add to Cart
        반응성: Human  
        신청: ELISA  
          10890-RP01-400
          10890-RP01-200
          10890-RP01-100
          400 µg 
          200 µg 
          100 µg 
          Add to Cart
          반응성: Human  
          신청: ELISA  
            10890-R211-50
            10890-R211-100
            50 µg 
            100 µg 
            Add to Cart
            반응성: Human  
            신청: ELISA  
              10890-MM04-50
              10890-MM04-200
              10890-MM04-100
              50 µg 
              200 µg 
              100 µg 
              Add to Cart
              반응성: Human  
              신청: ELISA  WB  
              • Slide 1
              10890-RP02-50
              10890-RP02-200
              10890-RP02-100
              50 µg 
              200 µg 
              100 µg 
              Add to Cart
              반응성: Human  
              신청: ELISA  
                10890-T16-50
                10890-T16-200
                10890-T16-100
                50 µg 
                200 µg 
                100 µg 
                Add to Cart
                반응성: Mouse  
                신청: ELISA  
                  50895-T16-50
                  50895-T16-200
                  50895-T16-100
                  50 µg 
                  200 µg 
                  100 µg 
                  Add to Cart

                  BAMBI/NMA ELISA Pair Set

                  검출 한계: 9.375 pg/ml
                  SEK10890-5
                  SEK10890-15
                  5 Plates 
                  15 Plates 
                  Add to Cart

                  BAMBI/NMA cDNA ORF CloneRelated Products

                  Related Products

                  Featured Reagent Products

                  BAMBI/NMA cdna-clone 연구배경

                  BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellular domain and a short cytoplasmic region that share sequence similarities with type 1 receptors, whose members have functions in signal transduction in various developing and pathological processes. BAMBI competes with the type 1 receptor, a receptor of the transforming growth factor-beta (TGF-beta), through functioning as negative regulators of TGF-beta by limiting the signaling range of the TGF-beta family during early embryogenesis. The expression of BAMBI can be induced by accumulated beta-catenin and BMP. The expression level of BAMBI was found aberrantly elevated in most colorectal and hepatocellular carcinomas relative to the corresponding non-cancerous tissues. It suggestes that beta-catenin and TGF-beta interfere growth arrest by inducing the expression of BAMBI, and this may contribute to colorectal and hepatocellular tumorigenesis.

                  휴먼 BAMBI/NMA cdna-clone 참고자료
                • Sekiya T, et al. (2003) Identification of BMP and Activin Membrane-bound Inhibitor (BAMBI), an Inhibitor of Transforming Growth Factor- Signaling, as a Target of the -Catenin Pathway in Colorectal Tumor Cells. The Journal of Biological Chemistry. 279:6840-6.
                • Shi YG, et al. (2003) Mechanisms of TGF- Signaling from Cell Membrane to the Nucleus. Cell. 113(6): 685-700.
                • Wanninger J, et al. (2011) Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes. FEBS Lett. 585(9):1338-44.
                • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".