Text Size:AAA

휴먼 CCL24/Eotaxin-2/MPIF-2 Gene ORF cDNA clone expression plasmid, N-Flag 태그

데이터시트리뷰프로토콜
발현 숙주: Baculovirus-Insect Cells  
  • Slide 1
10901-H08B-50
10901-H08B-20
50 µg 
20 µg 
Add to Cart
반응성: Human  
신청: ELISA  
    10901-T16-50
    10901-T16-200
    10901-T16-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    반응성: Human  
    신청: ELISA  
      10901-MM02-50
      10901-MM02-200
      10901-MM02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart

      CCL24/Eotaxin-2/MPIF-2 cDNA ORF CloneRelated Products

      Related Products

      Featured Reagent Products

      CCL24/Eotaxin-2/MPIF-2 cdna-clone 연구배경

      CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with aspirin-exacerbated respiratory disease.

      휴먼 CCL24/Eotaxin-2/MPIF-2 cdna-clone 참고자료
    • Manousou P, et al. (2010) Increased expression of chemokine receptor CCR3 and its ligands in ulcerative colitis: the role of colonic epithelial cells in in vitro studies. Clin Exp Immunol. 162 (2): 337-47.
    • Owczarek W, et al. (2010) Analysis of eotaxin 1/CCL11, eotaxin 2/CCL24 and eotaxin 3/CCL26 expression in lesional and non-lesional skin of patients with atopic dermatitis. Cytokine. 50 (2): 181-5.
    • Luesink M, et al. (2009) Chemokine induction by all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia: triggering the differentiation syndrome. Blood. 114 (27): 5512-21.
    • 주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".