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쥐 Transferrin/TF Gene ORF cDNA clone expression plasmid

데이터시트리뷰프로토콜
제품 설명: Active  
발현 숙주: Human Cells  
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11019-H08H-50
11019-H08H-100
50 µg 
100 µg 
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제품 설명:   
발현 숙주: Human Cells  
  • Slide 1
50817-M02H-50
50817-M02H-100
50 µg 
100 µg 
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제품 설명:   
발현 숙주: Human Cells  
  • Slide 1
50817-M08H-50
50817-M08H-100
50 µg 
100 µg 
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발현 숙주: Human Cells  
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80586-R08H-20
80586-R08H-100
20 µg 
100 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
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13656-W02H-20
13656-W02H-100
20 µg 
100 µg 
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제품 설명: Active  
발현 숙주: Human Cells  
  • Slide 1
13656-W08H-20
13656-W08H-100
20 µg 
100 µg 
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반응성: Human  
신청: ELISA  
    11019-R101-50
    11019-R101-100
    50 µg 
    100 µg 
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    반응성: Human  
    신청: 
      11019-MM01-50
      11019-MM01-200
      11019-MM01-100
      11019-MM01-1
      50 µg 
      200 µg 
      100 µg 
      1 mg 
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      반응성: Human  
      신청: ELISA  WB  IP  
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      • Slide 1
      11019-RP02-50
      11019-RP02-200
      11019-RP02-100
      50 µg 
      200 µg 
      100 µg 
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      반응성: Human  
      신청: ELISA  
        11019-MM06-50
        11019-MM06-200
        11019-MM06-100
        11019-MM06-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
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        반응성: Human  
        신청: ELISA  IHC-P  
        • Slide 1
        11019-MM03-50
        11019-MM03-200
        11019-MM03-100
        50 µg 
        200 µg 
        100 µg 
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        반응성: Human  
        신청: ELISA  
          11019-RP01-400
          11019-RP01-200
          11019-RP01-100
          400 µg 
          200 µg 
          100 µg 
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          반응성: Mouse  
          신청: IHC-P  
          • Slide 1
          50817-T08-50
          50817-T08-200
          50817-T08-100
          50 µg 
          200 µg 
          100 µg 
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          반응성: Mouse  
          신청: ELISA  
            50817-RP01-400
            50817-RP01-200
            50817-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            반응성: Rat  
            신청: ELISA  
              80586-RP01-400
              80586-RP01-200
              80586-RP01-100
              400 µg 
              200 µg 
              100 µg 
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              반응성: Rat  
              신청: ELISA  
                80586-T16-50
                80586-T16-200
                80586-T16-100
                50 µg 
                200 µg 
                100 µg 
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                Transferrin/TF ELISA Pair Set

                검출 한계: 15.6 pg/ml
                SEK11019-5
                SEK11019-15
                5 Plates 
                15 Plates 
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                Transferrin/TF cdna-clone 연구배경

                Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of Transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte / pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. Transferrins are iron binding transport proteins which bind Fe3+ ion in association with the binding of an anion, usually bicarbonate. This transferrin binds only one Fe3+ ion per protein molecule. Transports iron ions from the hemolymph into the eggs during the vitellogenic stage. Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. When a transferrin loaded with iron encounters with a transferring receptor on cell surface, transferring binds to it and, as a consequence, is transported into the cell in a visicle by receptor-mediated endocytosis. The PH is reduced by hydrogen iron pumps. The lower pH causes transferrin to release its iron ions. The receptor is then transported through the endocytic cycle back to the cell surface, ready for another round of iron uptake. Each transferrin molecule has the ability to carry two iron ions in the ferric form.

                 Transferrin/TF cdna-clone 참고자료
              • Ponka P, et al. (1998) Function and regulation of transferrin and ferritin. Semin Hematol. 35(1): 35-54.
              • Wagner E, et al. (1990) Transferrin-polycation conjugates as carriers for DNA uptake into cells. Proc Natl Acad Sci. 87(9): 3410-4.
              • Cheng Y, et al. (2004) Structure of the human transferrin receptor-transferrin complex. Cell. 116 (4): 565-76.
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