The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Antibiotic in Mammalian cell
Stable or Transient mammalian expression
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
HDAC11 cDNA ORF Clone, Human, C-OFPSpark® tag: Alternative Names
HD11 cDNA ORF Clone, Human
HDAC11 Background Information
Histone deacetylases (HDACs) are enzymes that regulate protein functions by catalyzing the removal of acetyl and acyl groups from lysine residues, which play pivotal roles in governing cell behaviors. HDAC11 knockout mice are resistant to high-fat diet-induced obesity and metabolic syndrome, suggesting that HDAC11 functions as a crucial metabolic regulator. HDAC11 as a novel regulator of obesity, with potentially important implications for obesity-related disease treatment. HDAC11 has therapeutic potential for treating diabetes mellitus-associated cardiac injury. Histone deacetylases (HDACs) are involved in multiple physical and pathological processes in classical Hodgkin lymphoma (cHL). HDAC11 was initially identified as a negative regulator of the well-known anti-inflammatory cytokine IL-1.
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