LILRB4/CD85k/ILT3  Protein, Antibody, ELISA Kit, cDNA Clone

LILRB4/CD85k/ILT3 Related Area

LILRB4/CD85k/ILT3 관련 경로

    LILRB4/CD85k/ILT3 요약 및 단백질 정보

    LILRB4/CD85k/ILT3 배경

    하부단위 구조: Binds PTPN6 when phosphorylated.
    도메인: Contains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
    세포하 위치: Cell membrane {ECO:0000269|PubMed:9151699}; Single-pass type I membrane protein {ECO:0000269|PubMed:9151699}. Note=Ligand binding leads to internalization and translocation to an antigen-processing compartment.
    조직 특이성: Detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. {ECO:0000269|PubMed:9151699, ECO:0000269|PubMed:9278324, ECO:0000269|PubMed:9548455}.
    유도: Upon contact with CD8(+)CD28(-) alloantigen-specific T suppressor (Ts) cells.
    염기서열 유사성: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. {ECO:0000305}.
    General information above from UniProt

    LILRB4/CD85k/ILT3 대체 이름

    ILT3,LIR5, [Human]

    LILRB4/CD85k/ILT3 관련 연구

    주의 : 모든 제품은 "연구 목적만을 위한 것이며 진단이나 치료에 사용하도록 의도되지 않았습니다".