CD204 / MSR1 Matched ELISA Antibody Pair Set,Human

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CD204 / MSR1 Matched ELISA Antibody Pair Set,Human General Information

Product name
CD204 / MSR1 Matched ELISA Antibody Pair Set,Human
Assay type
Solid Phase Sandwich ELISA
Specificity
Quantitative determination of Human CD204 / MSR1
Assay range
62.5-4000 pg/mL
Materials provided
1. Capture Antibody 0.5 mg/mL of mouse anti-Human MSR1 / CD204 monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: # 10427-MM03)
2. Detection Antibody 0.1 mg/mL of rabbit anti-Human MSR1 / CD204 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.4 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10427-R005)
3. Standard Each vial contains 40 ng of recombinant Human MSR1 / CD204. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 4000 pg/mL is recommended.
Product overview
This CD204 / MSR1 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human CD204 / MSR1 . It contains Human CD204 / MSR1 capture antibody, Human CD204 / MSR1 detector antibody (HRP) and a highly purified HEK293-expressed recombinant Human CD204 / MSR1 protein. This Pair Set is at affordable price for researchers.
Shipping
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
Storage
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

CD204 / MSR1 Matched ELISA Antibody Pair Set,Human Images

CD204 / MSR1 Matched ELISA Antibody Pair Set,Human: Alternative Names

CD204 Matched ELISA Antibody Pair Set, Human; phSR1 Matched ELISA Antibody Pair Set, Human; phSR2 Matched ELISA Antibody Pair Set, Human; SCARA1 Matched ELISA Antibody Pair Set, Human; SR-A Matched ELISA Antibody Pair Set, Human; SRA Matched ELISA Antibody Pair Set, Human

CD204 / MSR1 Background Information

Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1 and SCARA1, is a single-pass type II membrane protein which contains onecollagen-like domain and oneSRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer.
Full Name
macrophage scavenger receptor 1
References
  • Wang L. et al., 2003, Nat Genet. 35 (2): 128-9.
  • Chen Y.C. et al., 2008, Cancer Epidemiol Biomarkers Prev. 17 (4): 1001-3.
  • Shirato K. et al., 2009, Pflugers Arch. 459 (1): 93-103.
  • Sun J. et al., 2006, Prostate. 66 (7): 728-37.
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