RSPO3 cDNA Clone: Expression and Clone Vector / Plasmid

RSPO3 cDNA / Gene Overview

RSPO3 gene / cDNA is a protein-coding gene which located on 6q22.33. The RSPO3 gene is conserved in chimpanzee, Rhesus monkey, cow, mouse, rat, chicken, zebrafish, and frog.210 organisms have orthologs with human gene RSPO3.

RSPO3 cDNA / Gene Function

This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]

RSPO3 cDNA / Gene Sequence

LOCUS
LOCUS NM_032784 4583 bp mRNA linear PRI 29-JUL-2018
DEFINITION
Homo sapiens R-spondin 3 (RSPO3), mRNA.
ACCESSION
NM_032784
VERSION
NM_032784.4

This sequence information is just for reference only.

RSPO3 Family & Reagents

Gene family

RSPO3 Gene family reagents (Endogenous ligands)

Approved Symbol Reagent list
CCL22
GNRH2
XCL1
CCL16
THPO
CCL28
INHBB
CNTN1
IL11
GAL
Approved Symbol Reagent list
ICAM1
AGT
RSPO1
vWF
GDF10
PSAP
BID
PPBP
AMH
F2

RSPO3 cDNA / Gene Alias

  • FLJ14440

RSPO3 cDNA / Gene Expression

Broad expression in endometrium (RPKM 18.7), placenta (RPKM 8.3) and 14 other tissues