For cancer treatment, the initial method of chemotherapeutic agents has been cytotoxic drugs. Their action of mitotic inhibition is not limited to cancer cells, particularly profound effects being seen on the haematopoietic system, often with resulting neutropenia or pancytopenia. Targeted therapy conversely seeks to selectively affect cancer cells based on specific molecular characteristics. Targets for therapy are diverse but involve cellular growth, proliferation and, more recently, immune evasion. What is targeted therapy? Targeted therapy is a newer type of cancer treatment that uses drugs or other substances to more precisely identify and attack cancer cells, usually while doing little damage to normal cells.It has been validated to be a curative treatment for cancer, with many clinical trials and approved by FDA.
Charlton P, Spicer J. Targeted therapy in cancer[J]. Medicine, 2016, 44(1): 34-38.