VEGF / VEGFA / VEGF165 Neutralizing Antibody


VEGF / VEGFA / VEGF165 Neutralizing Antibody (Rabbit Monoclonal antibody) General Information

Product name
VEGF / VEGFA / VEGF165 Neutralizing Antibody
Validated applications
Species reactivity
Reacts with: Human
Has cross-reactivity with mouse VEGF164 (Catalog # 50159-MNAB) and rat VEGF164 (Catalog # 80006-RNAB) in ELISA assay
Recombinant Human VEGF165/VEGFA protein (Catalog#11066-HNAB)
This antibody was obtained from a rabbit immunized with purified, recombinant Human VEGF165/VEGFA (rh VEGF165/VEGFA; Catalog#11066-HNAB; P15692-4; Met1-Arg191) and was produced using recombinant antibody technology.
Monoclonal Rabbit IgG Clone #R012
Protein A
0.2 μm filtered solution in PBS
Please contact us for more information.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

VEGF / VEGFA / VEGF165 Neutralizing Antibody (Rabbit Monoclonal antibody) Validated Applications

Block: This VEGF Neutralizing Antibody can block the binding of recombinant VEGF (Catalog # 11066-HNAH) to its recombinant receptor VEGFR2 (Catalog # 10012-H08H) .
Neutralization: The neutralization activity of VEGF Neutralizing Antibody is measured by its ability to neutralize VEGF165 induced proliferation in HUVEC human umbilical vein endothelial cells. The Neutralization Titer (IC50) is typically 3.0-12.0 ng/mL in the presence of 10 ng/mL Recombinant Human VEGF165.
Please Note: Optimal concentrations/dilutions should be determined by the end user.

VEGF / VEGFA / VEGF165 Neutralizing Antibody (Rabbit Monoclonal antibody) Images

Cell Proliferation Induced by VEGF165 was Neutralized by Human VEGF Antibody. Recombinant Human VEGF165 (Catalog 11066-HNAB) stimulates proliferation in HUVEC human umbilical vein endothelial cells. Proliferation elicited by Recombinant Human VEGF165 (10 ng/mL ) is neutralized by increasing concentrations of Human VEGF neutralizing Monoclonal Antibody (Catalog 11066-R012). The IC50 is typically 3.0-12.0 ng/mL.

VEGF / VEGFA / VEGF165 Neutralizing Antibody: Alternative Names

Anti-MVCD1 Antibody; Anti-VEGF Antibody; Anti-VEGF165 Antibody; Anti-VPF Antibody

VEGFA Background Information

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.
Full Name
vascular endothelial growth factor A
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  • Eisenach PA, et al. (2010) MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src. J Cell Sci. 123(Pt 23):4182-4193.
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