MCP-5 (Protein | Antibody | cDNA Clone | ELISA Kit)

All MCP-5 reagents are produced in house and quality controlled, including 13 MCP-5 Gene, 1 MCP-5 Protein, 1 MCP-5 qPCR. All MCP-5 reagents are ready to use.

MCP-5 Protein (1)

    MCP-5 cDNA Clone (13)


    MCP-5 qPCR Primer (1)

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    MCP-5 Related Research Area

    MCP-5 Background

    Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impaired fibronectin and collagen deposition and indirectly stimulated collagen degradation through upregulation of matrix metalloproteinase-2. In post-MI patients, circulating LPS levels strongly associated with the Ccl12 homologue monocyte chemotactic protein 1 (MCP-1). Both MCP-1 and MCP-5 are HIF-1 target genes and that HIF-1alpha is involved in transcriptional induction of these two chemokines in astrocytes by hypoxia.