Anti-Nectin-2 Antibody (Rabbit Monoclonal antibody) General Information
Reacts with: Rat
Rat Nectin-2 No cross-reactivity in ELISA with Rat PVRL1
Recombinant Rat CD112 / Nectin-2 / PVRL2 protein (Catalog#80327-R08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD112 / Nectin-2 / PVRL2 (Catalog#80327-R08H; Q9ESS6; Met1-Gly351).
Monoclonal Rabbit IgG Clone #013
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Nectin-2 Background Information
Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.
poliovirus receptor-related 2 (herpesvirus entry mediator B)
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