Anti-CCR6 Antibody, Rabbit Polyclonal

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Anti-CCR6 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) General Information

Product name
Anti-CCR6 Antibody, Rabbit Polyclonal
Validated applications
WB
Species reactivity
Reacts with: Human
Specificity
Human CCR6
Immunogen
A synthetic peptide corresponding to the C-terminus of the Human CCR6
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human CCR6, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-CCR6 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
WB 1:500-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-CCR6 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Images

Anti-CD196 rabbit polyclonal antibody at 1:500 dilution

Lane A: MCF7 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti- Rabbit  IgG H&L (Dylight 800)  at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:42 kDa

Observed band size:42 kDa

Anti-CCR6 Antibody, Rabbit Polyclonal: Synonyms

Anti-BN-1 Antibody; Anti-C-CCKR-6 Antibody; Anti-CC-CKR-6 Antibody; Anti-CCR-6 Antibody; Anti-CD196 Antibody; Anti-CKR-L3 Antibody; Anti-CKRL3 Antibody; Anti-CMKBR6 Antibody; Anti-DCR2 Antibody; Anti-DRY6 Antibody; Anti-GPR29 Antibody; Anti-GPRCY4 Antibody; Anti-STRL22 Antibody

CCR6 Background Information

Chemokine receptors CCR6 and CCR7 have been reported to play important roles in T cell migration and organ-specific metastasis of various tumors. The expression levels of CCR6 and CCR7 in tumor tissues in patients with lymph node metastases than those without lymph node metastases. CCR6 and CCR7 expressions were also detected in metastatic lymph nodes. CCR6(+) subset of CD4(+) regulatory T cells, a newly characterized subset of Tregs, has been reported to contribute to local immune inhibition. There is a new subset of tumor-resident Tregs, CCR6(+) Tregs, may be dominantly responsible for the immunosuppression in tumor immunity and a potential predictor of the poor prognosis of breast cancer.
Full Name
chemokine (C-C motif) receptor 6

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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