Recombinant Anti-CD27 Antibody, Rabbit Monoclonal (Rabbit Monoclonal antibody) General Information
Recombinant Anti-CD27 Antibody, Rabbit Monoclonal
Reacts with: Human
Human CD27 No cross-reactivity in ELISA with Mouse CD27
Human TNFRSF8 / CD30
Human HVEM / TNFRSF14
Recombinant Human CD27 / TNFRSF7 Protein (Catalog#10039-H03H)
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD27 / TNFRSF7 (rh CD27 / TNFRSF7; Catalog#10039-H03H; Met 1-Ile 192; NP_001233.1).
Monoclonal Rabbit IgG Clone #036
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has important role in generation of T cell immunity, and is an apparently robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD7 on lymphocytes and dendritic cells. The CD27-CD7 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.
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