Anti-CLEC4D Antibody, Mouse Monoclonal

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Anti-CLEC4D Antibody, Mouse Monoclonal General Information

Product name
Anti-CLEC4D Antibody, Mouse Monoclonal
Validated applications
ELISA(Cap)
Species reactivity
Reacts with: Human
Specificity
Human CLEC4D
Immunogen
Recombinant Human CLEC4D Protein (Catalog#11485-H07H)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CLEC4D (rh CLEC4D; Catalog#11485-H07H; NP_525126.2; Gly52-Asn215). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG1 Clone #04
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-CLEC4D Antibody, Mouse Monoclonal Validated Applications

Notes
ELISA(Cap): This antibody will detect Human CLEC4D in ELISA pair set (Catalog: # SEK11485). In a sandwich ELISA, it can be used as capture antibody when paired with (Catalog: # 11485-T16).
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-CLEC4D Antibody, Mouse Monoclonal: Synonyms

Anti-CD368 Antibody; Anti-CLEC-6 Antibody; Anti-CLEC6 Antibody; Anti-CLECSF8 Antibody; Anti-Dectin-3 Antibody; Anti-MCL Antibody; Anti-MPCL Antibody

CLEC4D Background Information

C-type lectin (CLEC) family is a type of carbohydrate-binding protein domain named lectin. C-type lectins are the most diverse and prevalent lectin family in immunity with its requirement for calcium for binding. Proteins including a C-type lectin domain have diverse range of functions including cell-cell adhesion, immune response to pathogens and apoptosis. There are at least 14 types of C-type lectins: typeⅠto typeⅩⅣ. CLEC4D(CLECSF8) is a typeⅡ membrane glycoprotein belonging to the C-type lectin family, with restricted expression in the monocyte/macrophage lineage. It plays important roles in the function of macrophages.
Full Name
C-type lectin domain family 4, member D
References
  • Johnson KD, et al. (2007) Friend of GATA-1-independent Transcriptional Repression: A Novel Mode of GATA-1 Function. Blood. 109 (12): 5230-3.
  • Arce I, et al. (2004) The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. Eur J Immunol. 34 (1): 210-20.
  • Marshall AS, et al. (2006) Human MICL (CLEC12A) is differentially glycosylated and is down-regulated following cellular activation. Eur J Immunol. 36 (8): 2159-69.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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