Reacts with: Human Predicted to React with:
Mouse, Rat (Species predicted to react based on 100% sequence homology)
Human Connexin 43/GJA1
A synthetic peptide corresponding to the center region of the Human GJA1
This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human GJA1. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Monoclonal Rabbit IgG Clone #105
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
GJA1 encodes connexin 43 (Cx43), the most widely expressed gap junction protein. The de novo missense mutations in GJA1 (gap junction protein alpha 1) cause EKVP. Erythrokeratodermia variabilis et progressiva (EKVP) is a rare, inherited skin disease that is characterized by transient figurate patches of erythema, localized or generalized scaling, and frequent palmoplantar keratoderma. GJA1 and SERPINE2 represent potential gene markers associated with oocyte maturation. In the GJA1 gene which encodes gap junction channel protein connexin 43.
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