Anti-Cytokeratin 19/KRT19 Antibody, Mouse Monoclonal

1/3
Price:
Size:
Number:

Anti-Cytokeratin 19/KRT19 Antibody, Mouse Monoclonal (Mouse Monoclonal antibody) General Information

Product name
Anti-Cytokeratin 19/KRT19 Antibody, Mouse Monoclonal
Validated applications
IHC-P
Species reactivity
Reacts with: Human
Specificity
Human Cytokeratin 19/KRT19
Immunogen
A synthetic peptide corresponding to the center region of the Human KRT19
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the center region of the Human KRT19. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG3 Clone #08
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Cytokeratin 19/KRT19 Antibody, Mouse Monoclonal (Mouse Monoclonal antibody) Validated Applications

Application Dilution
IHC-P 1:250-1:1000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Cytokeratin 19/KRT19 Antibody, Mouse Monoclonal (Mouse Monoclonal antibody) Images

Immunochemical staining of human KRT19 in human thyroid cancer with mouse monoclonal antibody (1:500, formalin-fixed paraffin embedded sections).
Immunochemical staining of human KRT19 in human liver with mouse monoclonal antibody (1:500, formalin-fixed paraffin embedded sections).
Immunochemical staining of human KRT19 in human hepatoma with mouse monoclonal antibody (1:500, formalin-fixed paraffin embedded sections).

Anti-Cytokeratin 19/KRT19 Antibody, Mouse Monoclonal: Synonyms

Anti-CK19 Antibody; Anti-K19 Antibody; Anti-K1CS Antibody

Cytokeratin 19/KRT19 Background Information

Cytokeratin 19 (KRT19) is a cytoplasmic intermediate filament protein, which is responsible for structural rigidity and multipurpose scaffolds. In several cancers, KRT19 is overexpressed and may play a crucial role in tumorigenic transformation.The KRT19 gene encodes cytokeratin 19, an element of the cytoskeleton whose expression is frequently altered in renal cell carcinoma (RCC).KRT19 was identified as one of the key biomarkers for distinguishing cholangiocarcinoma (CCA) and hepatocellular carcinoma.Expression of KRT19 was specifically high in breast cancers and significantly correlated with their invasiveness. Moreover, knockdown of KRT19 led to increased proliferation, migration, invasion, drug resistance, and sphere formation in breast cancer cells via an upregulated NOTCH signaling pathway.
Full Name
keratin 19, type I

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

Add to Cart Successfully Add to Cart Failed Shopping cart is being updated, please wait U.S.A.