Anti-DEC-205 Antibody, Rabbit Polyclonal

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Anti-DEC-205 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) General Information

Product name
Anti-DEC-205 Antibody, Rabbit Polyclonal
Validated applications
IHC-P
Species reactivity
Reacts with: Human
Specificity
Human DEC-205
Immunogen
A synthetic peptide corresponding to the center region of the Human LY75 / DEC-205 / CD205
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human LY75 / DEC-205 / CD205, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-DEC-205 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
IHC-P 1:500-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-DEC-205 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Images

Immunochemical staining of human LY75 in human kidney with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Anti-DEC-205 Antibody, Rabbit Polyclonal: Synonyms

Anti-CD205 Antibody; Anti-CLEC13B Antibody; Anti-DEC-205 Antibody; Anti-GP200-MR6 Antibody; Anti-LY-75 Antibody

DEC-205 Background Information

LY75 knockdown in SKOV3 cells also resulted in predominant upregulation of functional pathways implicated in cell proliferation and metabolism, while pathways associated with cell signaling and adhesion, complement activation and immune response were mostly suppressed. Moreover, LY75 suppression had an opposite effect on EOC cell lines with epithelial phenotype (A278s and OV28), by directing epithelial-to-mesenchymal transition (EMT) associated with reduced capacity for in vivo EOC cell colonization, as similar/identical signaling pathways were reversely regulated, when compared to mesenchymal LY75 knockdown EOC cells.
Full Name
lymphocyte antigen 75

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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