Recombinant Anti-GITR Antibody, Rabbit Monoclonal General Information
Recombinant Anti-GITR Antibody, Rabbit Monoclonal
Reacts with: Human
Recombinant Human GITR/TNFRSF18/CD357 Protein (Catalog#13643-H08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Human GITR/TNFRSF18/CD357 (rh GITR/TNFRSF18/CD357; Catalog#13643-H08H; NP_683700.1; Met1-Glu161).
Monoclonal Rabbit IgG Clone #002
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.
Add to Cart SuccessfullyAdd to Cart FailedShopping cart is being updated, please waitU.S.A.
Successfully added to cart Please enter catalog numberSubmitted successfullyNetwork ErrorPlease enter your company namePlease enter your namePlease enter your emailPlease enter a valid email addressPlease enter some messageNot found.