Anti-GSTP1/GST3 Antibody, Rabbit Polyclonal

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Anti-GSTP1/GST3 Antibody, Rabbit Polyclonal General Information

Product name
Anti-GSTP1/GST3 Antibody, Rabbit Polyclonal
Validated applications
WB
Species reactivity
Reacts with: Human
Specificity
Human GSTP1/GST3
Immunogen
A synthetic peptide corresponding to the center region of the human GSTπ(GlutathioneS-Transferase,pi)
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the human GSTπ(GlutathioneS-Transferase,pi), and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-GSTP1/GST3 Antibody, Rabbit Polyclonal Validated Applications

Application Dilution
WB 1:500-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-GSTP1/GST3 Antibody, Rabbit Polyclonal Images

Anti-GSTπ(GlutathioneS-Transferase,pi) rabbit polyclonal antibody at 1:500 dilution

Lane A: Jurkat Whole Cell Lysate

Lane B: Hela Whole Cell Lysate

Lane C: K562 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:23 kDa

Observed band size:23 kDa

Anti-GSTP1/GST3 Antibody, Rabbit Polyclonal: Synonyms

Anti-DFN7 Antibody; Anti-FAEES3 Antibody; Anti-GST3 Antibody; Anti-GSTP Antibody; Anti-HEL-S-22 Antibody; Anti-PI Antibody

GSTP1/GST3 Background Information

Glutathione S-transferase (GST) family members promote carcinogenesis and cancer progression. GSTP1 levels correlated negatively with tumor size and serum alpha-fetoprotein (AFP) in HCC patients, and higher GSTP1 levels were associated with longer overall survival (OS) and disease-free survival (DFS), the high GSTP1 levels provide a better prognosis through suppression of tumorigenesis in HCC. Dual-testing of HPV and the GSTP1 might prove an effective screening tool for cervical cancer. GSTP1 is highly expressed in various cancerous cells and pre-neoplastic legions, where it is involved in apoptotic resistance or metabolism of several anti-tumor chemotherapeutics. That GSTP1 is a marker of malignant and pre-malignant cells and is a promising target for visualization and drug development. GSTP1 is a largely investigated tissue biomarker in several malignancies such as prostate, breast, lung, and hepatocellular carcinoma with good performances, especially for diagnostic purposes.
Full Name
glutathione S-transferase pi 1

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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