Anti-Insulin Antibody, Mouse Monoclonal
Cat: 11038-MM17
Anti-Insulin Antibody, Mouse Monoclonal General Information
Product name
Anti-Insulin Antibody, Mouse Monoclonal
Validated applications
IHC-P
Species reactivity
Reacts with: Human
Specificity
Human Insulin
Immunogen
Recombinant Human Insulin / INS Protein (Catalog#11038-HNAY)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Insulin / INS (rh Insulin / INS; Catalog#11038-HNAY; P01308; Phe1-Lys29 & Gly1-Asn21). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG1 Clone #17
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-Insulin Antibody, Mouse Monoclonal Validated Applications
| Application | Dilution |
|---|---|
| IHC-P | 1:500-1:2000 |
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-Insulin Antibody, Mouse Monoclonal Images
Immunochemical staining of human Insulin in human pancreas with mouse monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Citation List
Powered by BiozAnti-Insulin Antibody, Mouse Monoclonal: Synonyms
Anti-IDDM Antibody; Anti-IDDM1 Antibody; Anti-IDDM2 Antibody; Anti-ILPR Antibody; Anti-INS Antibody; Anti-IRDN Antibody; Anti-MODY10 Antibody
Insulin Background Information
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake.
Full Name
insulin
Related Pathways
-
AMPK Signaling Pathway -
Autophagy Pathway
References
- Veedfald S, Plamboeck A, Deacon C F, et al. Cephalic phase secretion of insulin and other enteropancreatic hormones in humans[J]. American Journal of Physiology-Gastrointestinal and Liver Physiology, 2016, 310(1): G43-G51.
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