Anti-Integrin beta 3 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) General Information
Anti-Integrin beta 3 Antibody, Rabbit Polyclonal
Reacts with: Human
Human Integrin beta 3
A synthetic peptide corresponding to the N-terminus of the human Integrin beta 3/ITGB3/CD61
Produced in rabbits immunized with A synthetic peptide corresponding to the N-terminus of the human Integrin beta 3/ITGB3/CD61, and purified by antigen affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Integrins containing the beta(3) subunit are key players in tumor growth and metastasis.ITGB3 plays an important role in ROS-induced migration and invasion in Colorectal cancer (CRC).ITGB3 is translationally activated in hypoxia and regulates malignant features, including epithelial-mesenchymal transition and cell migration, through the TGF-beta pathway, revealing a novel angle for the treatment of therapy-resistant hypoxic tumours.Bioinformatic algorithms and luciferase reporter assays revealed that integrin beta3 (ITGB3) is a direct target of miR-3a-5p.
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