Anti-Interferon alpha 2/IFNA2 Antibody, Mouse Monoclonal

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Anti-Interferon alpha 2/IFNA2 Antibody, Mouse Monoclonal General Information

Product name
Anti-Interferon alpha 2/IFNA2 Antibody, Mouse Monoclonal
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human Interferon alpha 2/IFNA2
Immunogen
Recombinant Human Interferon alpha 2/IFNA2 Protein (Catalog#13833-HNAY)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Interferon alpha 2/IFNA2 (rh Interferon alpha 2/IFNA2; Catalog#13833-HNAY; P01563.1; Cys24-Glu188). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG1 Clone #03
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Interferon alpha 2/IFNA2 Antibody, Mouse Monoclonal Validated Applications

Application Dilution
ELISA 1:1000-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Interferon alpha 2/IFNA2 Antibody, Mouse Monoclonal: Synonyms

Anti-IFN-alphaA Antibody; Anti-IFNA Antibody; Anti-IFNA2B Antibody; Anti-IFNAB Antibody; Anti-INFA2 Antibody; Anti-Interferon alpha 2 Antibody

Interferon alpha 2/IFNA2 Background Information

IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant.
Full Name
interferon, alpha 2
References
  • Wang, et al. (2004) Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E2. J Neuroimmunol. 156(1-2): 107-12.
  • Groopman JE, et al. (1984) Recombinant alpha-2 interferon therapy for Kaposi's sarcoma associated with the acquired immunodeficiency syndrome. Ann Intern Med. 100(5): 671-6.
  • Krueger JM, et al. (1987) Interferon alpha-2 enhances slow-wave sleep in rabbits. Int J Immunopharmacol. 9(1): 23-30.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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