Anti-IRF6 Antibody, Mouse Monoclonal

1/1
Price:
Size:
Number:

Anti-IRF6 Antibody, Mouse Monoclonal (Mouse Monoclonal antibody) General Information

Product name
Anti-IRF6 Antibody, Mouse Monoclonal
Validated applications
ICC/IF
Species reactivity
Reacts with: Human
Specificity
Human IRF6
Immunogen
A synthetic peptide corresponding to the C-terminus of the human IRF6
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the human IRF6. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG3 Clone #06
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-IRF6 Antibody, Mouse Monoclonal (Mouse Monoclonal antibody) Validated Applications

Application Dilution
ICC-IF 1:20-1:100
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-IRF6 Antibody, Mouse Monoclonal (Mouse Monoclonal antibody) Images

Immunofluorescence staining of Human IRF6 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with mouse anti-Human IRF6 monoclonal antibody (1:60) at 4℃ overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody(green). Positive staining was localized to cytoplasm and nucleus.

Anti-IRF6 Antibody, Mouse Monoclonal: Synonyms

Anti-LPS Antibody; Anti-OFC6 Antibody; Anti-PIT Antibody; Anti-PPS Antibody; Anti-PPS1 Antibody; Anti-VWS Antibody; Anti-VWS1 Antibody

IRF6 Background Information

Interferon regulatory factor 6 (IRF6), a member of the IRF family of transcription factors, is required for the differentiation of skin, breast epithelium, and oral epithelium. Interferon regulatory factor 6 (IRF6), the gene that causes van der Woude syndrome (VWS), is a candidate gene for nonsyndromic cleft lip with or without cleft palate (NSCLP) because a number of studies have supported an association between NSCLP and single nucleotide polymorphisms (SNPs) in IRF6 in several populations.Interferon Regulatory Factor 6 (IRF6) gene variants are significant genetic contributors to orofacial clefts.
Full Name
interferon regulatory factor 6
Related Pathways
  • NF-kB (NFkB) Pathway
    NF-kB (NFkB) Pathway

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

Add to Cart Successfully Add to Cart Failed Shopping cart is being updated, please wait U.S.A.