Anti-Desmin Antibody, Rabbit Polyclonal

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Anti-Desmin Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) General Information

Product name
Anti-Desmin Antibody, Rabbit Polyclonal
Validated applications
IHC-P
Species reactivity
Reacts with: Human, Mouse
Predicted to React with: Rat (Species predicted to react based on 100% sequence homology)
Specificity
Human Desmin
Immunogen
A synthetic peptide corresponding to the C-terminus of the human Desmin.
Preparation
Produced in rabbits immunized with A synthetic peptide corresponding to the C-terminus of the human Desmin., and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Desmin Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
IHC-P 1:500-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Desmin Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Images

Immunochemical staining DES in human prostate with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Immunochemical staining DES in human heart with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Immunochemical staining DES in mouse prostate with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Anti-Desmin Antibody, Rabbit Polyclonal: Synonyms

Anti-CSM1 Antibody; Anti-CSM2 Antibody; Anti-LGMD2R Antibody

Desmin Background Information

The cohesin loading factor, nipped-B-like protein (NIPBL), is also known as the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contribute to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation. Downregulation of NIPBL arrested cells in the G/G1 phase of the cell cycle and induced apoptosis and autophagy of breast cancer cells through the caspase3 and mammalian target of rapamycin (mTOR) signaling pathways. NIPBL, the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contribute to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation.
Full Name
desmin
Research Areas

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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