Anti-OTX2 Antibody, Rabbit Polyclonal

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Anti-OTX2 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) General Information

Product name
Anti-OTX2 Antibody, Rabbit Polyclonal
Validated applications
WB
Species reactivity
Reacts with: Human
Predicted to React with: Mouse (Species predicted to react based on 100% sequence homology)
Specificity
Human OTX2
Immunogen
A synthetic peptide corresponding to the center region of the Human OTX2 / CPHD6
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human OTX2 / CPHD6, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-OTX2 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
WB 1:500-1:1000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-OTX2 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Images

Anti-OTX2 rabbit polyclonal antibody at 1:500 dilution

Lane A: Jurkat Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:32 kDa

Observed band size:43 kDa

(We are unsure as to the identity of these extra bands.)

Anti-OTX2 Antibody, Rabbit Polyclonal: Synonyms

Anti-CPHD6 Antibody; Anti-MCOPS5 Antibody

OTX2 Background Information

OTX2 is the member of a highly conserved family of bicoid-like homeodomain transcription factors responsible for the regulation of cerebellar development.Orthodenticle homeobox 2 (OTX2) controls essential, homeostatic retinal pigment epithelial (RPE) genes in the adult.Mutations in OTX2 are mostly identified in patients with anophthalmia/microphthalmia with variable severity. The OTX2 homeobox gene plays a crucial role in craniofacial morphogenesis during early embryo development. Otx2 knockout embryos fail to form a head.The Otx2 homeodomain transcription factor is essential for gastrulation and early neural development.
Full Name
orthodenticle homolog 2

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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