Anti-CD302 Antibody, Rabbit Polyclonal

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Anti-CD302 Antibody, Rabbit Polyclonal General Information

Product name
Anti-CD302 Antibody, Rabbit Polyclonal
Validated applications
ELISA
Species reactivity
Reacts with: Mouse
Specificity
Mouse CD302
Immunogen
Recombinant Mouse CD302 / CLEC13A protein (Catalog#50706-M08H)
Preparation
Produced in rabbits immunized with purified, recombinant Mouse CD302 / CLEC13A (Catalog#50706-M08H; Q9DCG2-2; Met1-His156). CD302 / CLEC13A specific IgG was purified by Mouse CD302 / CLEC13A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-CD302 Antibody, Rabbit Polyclonal Validated Applications

Application Dilution
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-CD302 Antibody, Rabbit Polyclonal: Synonyms

Anti-1110055L24Rik Antibody; Anti-AI159627 Antibody

CD302 Background Information

CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.
Full Name
CD302 molecule
References
  • Kato M, et al. (2007) The novel endocytic and phagocytic C-Type lectin receptor DCL-1/CD302 on macrophages is colocalized with F-actin, suggesting a role in cell adhesion and migration. J Immunol. 179(9): 6052-63.
  • Skinnider BF, et al. (2002) The role of cytokines in classical Hodgkin lymphoma. Blood. 99(12): 4283-97.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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