Anti-UQCRC2 Antibody, Rabbit Polyclonal

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Anti-UQCRC2 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) General Information

Product name
Anti-UQCRC2 Antibody, Rabbit Polyclonal
Validated applications
IHC-P,ICC/IF
Species reactivity
Reacts with: Human, Cynomolgus
Specificity
Human UQCRC2
Immunogen
E. coli-derived Human UQCRC2 fragment
Preparation
Produced in rabbits immunized with E. coli-derived Human UQCRC2 fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Anti-UQCRC2 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
IHC-P 1:50-1:200
ICC-IF 1:50-1:200
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-UQCRC2 Antibody, Rabbit Polyclonal (Rabbit Polyclonal antibody) Images

Immunochemical staining of human UQCRC2 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Immunochemical staining of human UQCRC2 in cynomolgus heart with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Immunofluorescence staining of UQCRC2 in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Human UQCRC2 polyclonal antibody (dilution ratio 1:100) at 4℃ overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm.

Anti-UQCRC2 Antibody, Rabbit Polyclonal: Synonyms

Anti-MC3DN5 Antibody; Anti-QCR2 Antibody; Anti-UQCR2 Antibody

UQCRC2 Background Information

Ubiquinol-cytochrome-c reductase core protein 2 (UQCRC2) is a component of ubiquinol-cytochrome c reductase complex that is known to correlate with male fertility via spermatogenesis. Simultaneously, nutlin-3a is a small molecule antagonist of mouse double minute 2 repressor (MDM2), activate p53 and induce apoptosis responsible for spermatogenesis. UQCRC2 can also interactive with NLRX1, the only member of the Nod-like receptor (NLR) family, providing a molecular basis for the role of NLRX1 in ROS generation.
Full Name
ubiquinol-cytochrome c reductase core protein II

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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