G Protein-Coupled Receptors (GPCRs)

G protein-coupled receptors (GPCRs),G-protein linked receptors, serpentine receptors, or heptahelical receptors are the largest superfamily of membrane proteins in the human genome and they are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to peptides and large proteins – GPCRs undergo a conformational change that activates heterotrimeric G proteins (guanine nucleotide-binding proteins), which are important for transmitting the extracellular, ligand signal to the cell interior. G-Proteins can be classified by homologous structure and via common ligand subtypes.

Sino Biological lists the classification tree of G Protein-Coupled Receptors (GPCRs), click to see all the related molecules/targets and research reagents of them.

G Protein-Coupled Receptors (GPCRs)

G Protein-Coupled Receptors (GPCRs)

Bioactive Lipid G Protein-Coupled Receptors

Bioactive Lipid G Protein-Coupled Receptors

Orphan G Protein-Coupled Receptors

Orphan G Protein-Coupled Receptors

Other G Protein-Coupled Receptors

Other G Protein-Coupled Receptors

Peptide Hormone G Protein-Coupled Receptors

Peptide Hormone G Protein-Coupled Receptors