C6 cDNA Clone: Expression and Clone Vector / Plasmid

C6 cDNA / Gene Overview

C6 gene / cDNA is a protein-coding gene which located on 5p13.1. The C6 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.233 organisms have orthologs with human gene C6.

C6 cDNA / Gene Function

This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]

C6 cDNA / Gene Sequence

LOCUS
LOCUS NM_000065 3722 bp mRNA linear PRI 25-JUN-2018
DEFINITION
Homo sapiens complement C6 (C6), transcript variant 1, mRNA.
ACCESSION
NM_000065
VERSION
NM_000065.3

This sequence information is just for reference only.

C6 Family & Reagents

C6 Gene family reagents (Complement system)

Approved Symbol Reagent list
C1QB
C5
CD46
CFB
CFH
CFHR2
Approved Symbol Reagent list
C2
C7
CD59
CFD
CFHR1
CR2

C6 Gene family reagents (Sushi domain containing)

Approved Symbol Reagent list
APOH
C7
CD55
CFH
CFHR2
F13B
IL2RA
SELE
SELP
SUSD4
Approved Symbol Reagent list
C2
CD46
CFB
CFHR1
CR2
HP
PAPPA2
SELL
SEZ6L2
TPO

C6 cDNA / Gene Expression

Biased expression in liver (RPKM 126.4), heart (RPKM 11.8) and 2 other tissues