CA5A Proteins, Antibodies, cDNA Clones Research Reagents

All CA5A reagents are produced in house and quality controlled, including 1 CA5A Antibody, 15 CA5A Gene, 1 CA5A Protein, 2 CA5A qPCR. All CA5A reagents are ready to use.

CA5A Protein (1)

    CA5A Antibody (1)

      CA5A cDNA Clone (15)

      CA5A Background

      Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA5A / CA-VA is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. It is inhibited by coumarins, sulfonamide derivatives such as acetazolamide and Foscarnet (phosphonoformate trisodium salt).

      CA5A References

      • Strausberg, R.L. et al., 2002, Proc. Natl. Acad. Sci. USA 99:16899 - 903.
      • Liao, S.Y. et al., 2003, J. Med. Genet. 40:257 - 262.
      • Temperini C.et al., 2006, Chemistry 12: 7057-66.
      • Temperini C.et al., 2006, J. Med. Chem. 49: 3019-27.
      • Supuran, C. T. et al., 2008, Curr Pharm Des. 14 (7): 601-602.
      • Elleuche, S. et al., 2009, Curr Genet. 55 (2): 211-222.

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