Coronavirus Nucleocapsid Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All Coronavirus Nucleocapsid reagents are produced in house and quality controlled, including 16 Coronavirus Nucleocapsid Antibody, 1 Coronavirus Nucleocapsid ELISA, 17 Coronavirus Nucleocapsid Gene, 11 Coronavirus Nucleocapsid IP Kit, 4 Coronavirus Nucleocapsid Lysate, 11 Coronavirus Nucleocapsid Protein. All Coronavirus Nucleocapsid reagents are ready to use.

Coronavirus Nucleocapsid Antibody (16)

    Coronavirus Nucleocapsid ELISA Kit & Match Antibody ELISA Pair Set (1)

    Coronavirus Nucleocapsid cDNA Clone (17)

    2019-nCoV

    In expression vector

    SARS-CoV-2
    SARS-CoV,Strain Tor2

    In expression vector

    In lentiviral vector

    MERS-CoV

    In expression vector

    Coronavirus Nucleocapsid Lysate (4)

      Coronavirus Nucleocapsid Background

      Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

      Coronavirus Nucleocapsid References

        1. 1.Van Boheemen S, et al. (2012), MBio. 3(6):e00473-12.
        2. Bisht H. et al., 2004, Proc Natl Acad Sci. 101 (17): 6641-6.
        3. Li W. et al., 2005, Science. 309 (5742): 1864-8.

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